Motival Tablets in Pakistan

Motival Tablets in Pakistan

Motival is a Combination Medication Containing Nortriptyline (10 Mg) and **fluphenazine Hcl (0.5 Mg) Per Coated Tablet.

What It is Used for

According to One Manufacturer Leaflet: For the Treatment of Mild to Moderate Mixed Anxiety-depressive States.
Other Sources (Pharmacy Listings) State Use in Psychotic Disorders, Especially Schizophrenia, With Symptoms Such as Hallucinations, Delusions, Abnormal Behavior.
Some Older Clinical Studies Have Used It in Anxiety or Anxiety + Depression.

How It Works

Nortriptyline Increases Levels of Certain Mood-related Neurotransmitters (Such as Norepinephrine, and to Some Extent Serotonin) by Blocking Their Reuptake.
Fluphenazine Blocks Dopamine (D2) Receptors and Thereby Reduces Psychotic Symptoms (Hallucinations, Delusions) and Affects Mood/behavior.
The Idea of Combining an Antidepressant and Antipsychotic May Allow Treating a Mixed Condition of Mood/anxiety + Psychotic Features.

Dosage & Administration

One Manufacturer Reference: Adults: 1 Tablet Three Times Daily. Maximum Course Limited to 3 Months; if No Response After 4 Weeks, Switch Treatment.
The Actual Prescribing Doctor May Adjust Dose Based on Patient’s Condition, Response, Tolerance, Comorbidities and Other Medications.

Important Precautions & Warnings

Because Fluphenazine (Antipsychotic) and Nortriptyline (Tricyclic Antidepressant) Both Carry Serious Potential Side-effects, Caution is Required.
Contraindications / Situations of Caution Include: Severe Depression, Blood Disorders, Kidney or Liver Failure, Coma, Severe Cardiovascular Insufficiency, Marked Cerebral Atherosclerosis.